Comment on ‘Evaluation of Pain in Infants of the First 100 Days of Age With Artificial Intelligence Techniques’

Evaluation of Pain in Infants of the First 100 Days of Age With Artificial Intelligence Techniques by Acikgoz et al., which presents an artificial intelligence (AI)-based model for neonatal pain assessment [1].The authors address an important clinical challenge, as objective pain assessment in neonates remains difficult because of their inability to verbally communicate.We congratulate the authors on their innovative work while highlighting several methodological considerations that may influence the transparency, clinical applicability, and generalizability of the proposed model.