Impact of clinical manifestations of vitiligo on patients’ quality of life of patients

Vitiligo is classified as an acquired hypomelanosis with a genetic predisposition to autoimmune reactions. The disease presents with focal depigmentation. Vitiligo is often mistakenly regarded as a cosmetic defect, and proper examination and treatment are neglected. The clinical manifestations of the disease have a significant impact on patients’ quality of life. This article is devoted to a comprehensive analysis of the psychosocial aspects of vitiligo and their impact on patients’ quality of life. In addition to investigating the etiology, pathogenesis, and clinical manifestations of the disease, the psychological status and quality of life of patients are considered in detail. Particular attention is paid to factors determining the degree of quality of life impairment in vitiligo, including gender differences, age, lesion location, and the patient’s socioeconomic status. It has been established that the presence of depigmentation lesions on exposed areas of the body significantly exacerbates the psychological burden of the disease and impedes patients’ social adaptation. The results of large international studies, demonstrating the significant impact of vitiligo on the emotional state and social adaptation of patients, are presented. This article highlights the need for a comprehensive approach to vitiligo management, including not only dermatological but also psychological support. The findings can be used to develop effective treatment and support strategies for patients with vitiligo.