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This study investigates the impact of enterprise Artificial Intelligence (AI) applications on the integration of regional industrial and innovation chains. Utilizing data from 297 Chinese prefecture-level cities (2013–2022) and employing coupling analysis and mediation models, the research demonstrates that enterprise AI significantly facilitates "dual-chain" integration. This process is primarily driven by digital infrastructure upgrading and enhanced technological innovation levels. Heterogeneity analysis reveals that this positive impact is more pronounced in regions with high fiscal self-sufficiency and among large to medium-sized enterprises, with significant effects observed in eastern and central China. Conversely, the impact remains limited in the western region and among small-scale firms due to resource and institutional constraints. The findings suggest that fostering a synergistic digital ecosystem and implementing inclusive technology empowerment are crucial for achieving high-quality regional development.
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Li et al. (2026) studied this question.
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