Surgical Management and Defect-Based Reconstruction of Eyelid Sebaceous Gland Carcinoma: A Case Series of Four Patients

Background: Sebaceous gland carcinoma (SGC) is an uncommon, potentially aggressive eyelid malignancy. Management requires histopathological confirmation, assessment of tumour clearance and reconstruction that addresses the anatomical and functional requirements of the resulting defect.Objective: To describe the clinical characteristics, excision and reconstructive approaches in four patients with eyelid SGC.Methods: This descriptive case series includes four patients with histopathologically suggestive eyelid sebaceous gland carcinoma (SGC). Demographic details, lesion location and dimensions, excision and reconstruction techniques, surgical margin status, PET-CT findings and follow-up were summarized from the available clinical information.Results: The series included three women aged 35, 65 and 67 years and one man aged 50 years. Two lesions involved the upper eyelid and two involved the lower eyelid near the lacrimal punctum. Lesion dimensions ranged from 10 ×10 mm to 25 × 15 mm. Reconstruction comprised direct closure, a Cutler–Beard procedure, laissez-faire healing and a Tenzel semicircular flap, one technique per case. Histopathology was suggestive of SGC in all four cases, and surgical margins were free of tumour. PET-CT was negative for metastasis. All patients were followed for three years and had good reported cosmesis. No Recurrence , Good eyelid closurenoted in all four patients.Conclusion: This four-case series illustrates individualized eyelid reconstruction after excision of SGC. All cases had tumour-free margins, negative PET-CT findings for metastasis and three years of follow-up, with good reported cosmesis.