Structural Characterization of 1-(2-(2,8-bis(Trifluoromethyl)quinolin-4-yl)-2-hydroxyethyl)pyrrolidin-2-one: An Unexpected Cyclization Product

1-(2-(2,8-bis(Trifluoromethyl)quinolin-4-yl)-2-hydroxyethyl)pyrrolidin-2-one has been synthesized through a multi-step pathway starting from commercially available 4-hydroxy-2,8-bis(trifluoromethyl)quinoline. Structural characterization of this original substituted mefloquine derivative was achieved using FT-IR, 1H-NMR, 13C-NMR and single-crystal X-Ray diffraction analysis.