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The article examines the molecular genetic mechanisms of colorectal cancer (CRC) carcinogenesis. It is shown that CRC development is a complex multi-stage process. According to the current understanding, CRC represents a heterogeneous group of neoplasms that develop via several carcinogenesis pathways. Understanding the molecular mechanisms of carcinogenesis is important not only for researchers in this field, but also for related specialists, such as endoscopists. The study of neoplasms makes it clear what to do in cases of hereditary syndromes or sporadic cases: what extent of surgery should be performed.
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Шубин et al. (2026) studied this question.
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