Spontaneous corneal perforation against the background of mycotic fusarium endophthalmitis (clinical case)

The most common etiology of infectious endophthalmitis is usually bacterial or fungal. The main ways of infection penetration into the eyeball: exogenous (trauma, complication of surgical intervention on the eyeball) or endogenous (dissemination of infection in septic processes, hematogenous spread). The most common pathogens of mycotic endophthalmitis are Candida spp., Aspergillus spp. and Fusarium spp. Diagnosis of fungal processes is labor-intensive and not always available. Often, patients undergo long-term treatment before perfect diagnosis. Ethiotropic treatment includes the use of antimycotic druds and surgical methods. The article presents a clinical observation of a long-term course of mycotic endophthalmitis caused by Fusarium spp. with an outcome in spontaneous perforation of the eyeball. Keywords: Fusarium spp.; antimycotic therapy; voriconazole; posaconazole; mycotic endophthalmitis; fusarium; endophthalmitis