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Chondrosarcoma (CS) is a rare tumor condition of varying grades and with variable biological behaviors, capable of producing cartilaginous material; these tumors can develop most frequently in the pelvis, skull base, and axial skeleton, being the second most common bone tumor.These neoplasms encompass a heterogeneous spectrum ranging from low-grade indolent lesions to aggressive neoplasms with high metastatic potential.Its high degree of development consists of multiple genetic instability events (COL2A1, ACAN, and COMP) and cellular components such as fibroblasts that favor the marked increase in chondroid material.Due to its variable growth rate, the clinical presentation of chondrosarcoma is usually insidious, which sometimes hinders an early diagnosis.In the present article, a patient is presented with a tumor and peripheral nervous symptoms that led to a surgical procedure in which a diagnosis of grade 1 chondrosarcoma (CS1) was made.
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Peña et al. (2026) studied this question.
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