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Objective This study examined the efficacy and safety of mindfulness-based stress reduction (MBSR) for menopause-related insomnia symptoms, with a focus on anxiety, depression, sleep quality, coping styles and quality of life.Method Eighty-two patients with menopause-related insomnia symptoms were randomized into an experimental group (n = 41, MBSR plus routine health intervention) and a control group (n = 41, routine health intervention) for a 12-week intervention. Emotional state, sleep quality, disease coping styles and quality of life were assessed using standardized scales, with intervention adherence and adverse events recorded as secondary outcomes.Results Compared with routine care alone, the MBSR group achieved significantly larger decreases in Self-Rating Anxiety Scale and Self-Rating Depression Scale scores, lower Pittsburgh Sleep Quality Index scores, more positive improvements in disease coping styles and more pronounced gains in several quality-of-life dimensions, particularly physical, psychological and social functioning (p < 0.01). The experimental group had high offline and online adherence rates, with no significant between-group differences in adherence (p > 0.05). The adverse event incidence was below 5% in both groups, with no serious adverse events reported.Conclusion This study confirms that 12-week MBSR is a safe and effective intervention for improving sleep quality, negative emotions, coping styles and quality of life in patients with menopause-related insomnia symptoms.
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Zhao et al. (2026) studied this question.
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