Adult Salmonella Infections: A 10-Year Clinical Experience in a Tertiary Care Center

Background: Salmonella infections are an important cause of foodborne illness and may present with a broad clinical spectrum, ranging from mild gastroenteritis to invasive systemic infections.This study aimed to evaluate the epidemiological, clinical, and microbiological characteristics of Salmonella infections in adults at a tertiary care center. Materials and Methods:In this retrospective study, patients aged ≥18 years with Salmonella spp.isolated from clinical specimens between January 2014 and December 2023 were included.Demographic data, clinical findings, culture results, and antimicrobial susceptibility profiles were evaluated using the hospital electronic database.Results: A total of 82 adult patients were included.Of the patients, 53.7% were male and the mean age was 53.1 ± 20.46 years.Acute enteritis was the most common clinical presentation (56.1%).Salmonella was most frequently isolated from stool samples (67.2%).Bacteremia was detected in 15.9% of the patients.Clinically confirmed urinary tract infections were identified in three patients, while various extraintestinal infections were also observed.Most cases occurred during the summer months (54.9%).Ciprofloxacin resistance among Salmonella isolates was notable.Conclusion: Salmonella infections in adults encompass a broad clinical spectrum, ranging from self-limited gastroenteritis to invasive bacteremia and focal extraintestinal infections.Invasive disease occurred particularly among older and immunosuppressed patients; the notable ciprofloxacin resistance observed in our region underscores the importance of continuous regional surveillance of antimicrobial resistance to guide empirical treatment strategies.