Current Approaches to Geriatric Immunizat?on: A Narrative Mini-Review

As the global population ages, the implementation of a "life-course immunization" approach has become a critical pillar for maintaining functional capacity and ensuring healthy aging. Current 2025-2026 guidelines emphasize a strategic transition to trivalent influenza vaccines and the routine administration of novel Respiratory Syncytial Virus vaccines for high-risk geriatric cohorts. Furthermore, clinical protocols prioritize high-dose or adjuvanted formulations to overcome immunosenescence and provide robust protection against invasive pneumococcal disease, herpes zoster, and COVID-19 subvariants. Despite these advancements, significant disparities in vaccine access and public awareness persist, particularly in low- and middle-income countries. Strengthening national immunization schedules through the integration of these next-generation vaccines is essential to alleviate the burden on healthcare systems and reduce preventable mortality. Ultimately, the shift toward personalized immunization strategies aims to ensure that every older adult achieves optimal seroprotection and a higher quality of life.