Successful Use of 308 nm Excimer Pulsed Light in the Treatment of Hailey-Hailey Disease

We describe the cases of two female patients with Hailey- Hailey disease (HHD), who showed significant improvement after treatment with 308 nm Excimer Pulsed Light (EPL). Both patients reported reduced frequency, severity, and duration of flares, along with decreased pain and pruritus. These cases suggest that EPL may be an effective, well tolerated therapeutic option for HHD, especially in patients who may not tolerate, or may be unsuitable for systemic treatments.