Answers are grounded in this paper and cite their sources.
Isolated bilateral renal metastasis from esophageal squamous cell carcinoma (ESCC) is extremely rare. We report a 63-year-old man with ESCC treated with neoadjuvant chemoimmunotherapy and esophagectomy followed by anti-PD-1 maintenance, in whom follow-up 18 F-FDG PET/CT demonstrated multiple bilateral renal lesions with intense 18 F-FDG uptake. CT-guided biopsy confirmed metastatic squamous cell carcinoma. This case highlights that new isolated renal lesions during cancer immunotherapy should not be assumed to be immune-related nephritis and underscores the value of 18 F-FDG PET/CT and biopsy in establishing the diagnosis.
No takes yet. Share an insight, caveat, or question.
Tan et al. (2026) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: