Nevus Lipomatosus Superficialis: A Rare Benign Skin Lesion – A Case Report

Background: Nevus lipomatosus superficialis is a rare benign skin hamartoma which consists of mature fat tissue in the superficial dermis without connection to the subcutaneous fat.They usually appear as soft yellowish or skin-colored papules or nodules with a predilection for the buttocks, thighs, and lower back.Diagnosis is by histopathological examination.Case: We report a 46-year-old female who presented to the primary care clinic with two (pedunculated and sessile) nodular skin lesions in the upper inner thighs.The patient reported that lesions had been present for about 10 years and desired to have them removed for cosmetic reasons.On exam, there was a flesh colored 1.5 x 1 cm sessile lesion on the right inner thigh and a wider-based 2.5 x 2 cm pedunculated lesion on the left inner thigh, similar to Figure 1.An excisional shave biopsy was performed, which established the diagnosis.Conclusion: This skin lesion is rare and commonly misinterpreted as any of its differential diagnoses, such as skin tags, lipofibroma, hemangioma, lymphangioma, and neurofibroma.Increasing awareness of this skin lesion among primary care physicians will assist with diagnosis and curative treatment when desired.