Endoscopic Ultrasound in Patients with Cardiovascular Diseases: Periprocedural Risk Stratification, Cardiovascular Findings, and Interventional Management

Q: What is the clinical evidence from this study?

Study design: Review. Population: Cardiovascular diseases. Intervention: Endoscopic ultrasound (EUS).

Q: What does this research mean for the field?

Endoscopic ultrasound provides high-resolution visualization and feasible interventional capabilities for cardiovascular pathologies, but requires specialized periprocedural management and prospective validation. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

Jingshuang Yan; Chen Mu; Yanzhi Wang; Qianqian Wang; Xu Guo

doi:10.1016/j.gande.2026.11.006

November 1, 2026Gastroenterology & EndoscopyOpen Access

Endoscopic Ultrasound in Patients with Cardiovascular Diseases: Periprocedural Risk Stratification, Cardiovascular Findings, and Interventional Management

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Key result

Endoscopic ultrasound shows emerging diagnostic and interventional utility in cardiovascular care, but prospective trials are needed.

Why the study?

The application of endoscopic ultrasound has expanded into the cardiovascular system for both diagnosis and treatment, but no prior review had summarized its role in this field.

Key Points

To review the evolving diagnostic and interventional applications of endoscopic ultrasound in patients with cardiovascular diseases alongside essential periprocedural risk stratification strategies.
Narrative review synthesizing published evidence and case reports on endoscopic ultrasound use, cardiovascular diagnostic capabilities, and interventional techniques.
Identifies antithrombotic regimens, anesthesia strategies, and hemodynamic stability as primary periprocedural safety considerations in cardiovascular patients undergoing endoscopy.
Demonstrates high-resolution imaging capability for occult cardiovascular lesions and technical feasibility for interventions including endoscopic ultrasound-guided tissue acquisition and posterior pericardial drainage.
Reports that prospective multicenter trials and standardized clinical pathways are lacking but essential to validate interventional efficacy and safety.

Structured PICO

P

Population

Patients with cardiovascular diseases undergoing endoscopic ultrasound (EUS), including high-risk cardiovascular patients

I

Intervention

Endoscopic ultrasound (EUS), including periprocedural management (antithrombotic, anesthesia, and hemodynamic management), diagnostic visualization, EUS-guided tissue acquisition, and posterior pericardial drainage

This narrative review outlines the emerging role of endoscopic ultrasound in cardiovascular care, highlighting periprocedural risk management, incidental diagnostic capabilities, and novel interventional applications such as posterior pericardial drainage.

Limitations

Interventional applications are currently described mainly in case reports
Multicenter prospective studies and standardized periprocedural protocols are lacking to establish safety and efficacy
Interventional applications are currently limited to several case reports
Lack of multicenter prospective studies
Lack of standardized periprocedural protocols

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Implication

EUS may aid cardiovascular diagnostics and interventions with safety vigilance; leaves open prospective validation of efficacy and standardized protocols.

Abstract

Endoscopic ultrasound (EUS) has evolved from a diagnostic tool into a platform that combines diagnosis and treatment. Its application has expanded beyond the digestive system and continuous to emerge in the cardiovascular system. However, there is no review on its application in this field. This narrative review provides an overview of EUS in cardiovascular diseases following a clinical decision pathway. For periprocedural safety, antithrombotic management is a key focus during endoscopy procedures, as well as anesthesia and hemodynamic management in high-risk cardiovascular patients. In terms of cardiovascular findings, EUS enables high-resolution visualization and incidental detection of occult pathologies. Exploring interventional applications, several case reports describe the technical feasibility of EUS-guided tissue acquisition and posterior pericardial drainage. This narrative review provides an overview of the periprocedural management of EUS procedure, and its incremental value in diagnostic and interventional therapy. While EUS holds broad prospects for cardiovascular care, multicenter prospective studies and standardized periprocedural protocols are urgently required to establish its safety and efficacy.

Discussion

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Cite This Study

Yan et al. (2026) conducted a review in Cardiovascular diseases. Endoscopic ultrasound (EUS) was evaluated. Endoscopic ultrasound offers incremental diagnostic and interventional value in cardiovascular diseases, though multicenter prospective studies are needed to establish safety and efficacy.

synapsesocial.com/papers/6af88c410e4d8f4b089c1aa2 https://doi.org/10.1016/j.gande.2026.11.006

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Endoscopic Ultrasound in Patients with Cardiovascular Diseases: Periprocedural Risk Stratification, Cardiovascular Findings, and Interventional Management

Key Points

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Endoscopic Ultrasound in Patients with Cardiovascular Diseases: Periprocedural Risk Stratification, Cardiovascular Findings, and Interventional Management

Key Points

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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