Key result
Severe systemic sclerosis calcinosis rarely manifests as calcific pericardial effusion with early constriction.
Why the study?
Calcific pericardial effusion with early signs of constriction is an extraordinarily rare manifestation of systemic sclerosis, with only nine cases previously reported in the medical literature.
Highlights an extraordinarily rare cardiac manifestation of systemic sclerosis—calcific pericardial effusion with early signs of constriction—with only nine prior cases reported in the medical literature.
Answers are grounded in this paper and cite their sources.
Clinicians should consider calcific pericardial effusion in systemic sclerosis with calcinosis; this case extends sparse literature but leaves open questions on prevalence and management.
We report the case of a woman with diffuse systemic sclerosis and severe universal calcinosis who developed calcific pericardial effusion with early signs of constriction. This case highlights an extraordinarily rare manifestation with only nine cases reported in the medical literature to date.
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Ampuero et al. (2026) studied this question. Diffuse systemic sclerosis with severe universal calcinosis can rarely manifest as calcific pericardial effusion with early signs of constriction.
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