Best Evidence for Bladder Function Exercise in Patients With Bladder Cancer Following Orthotopic Neobladder Reconstruction

Objectives This evidence summary aimed to synthesize the best evidence for bladder function exercise in patients with bladder cancer after undergoing ONB reconstruction. Methods This review was conducted in accordance with the evidence summary report standards established by the Fudan University Center for Evidence-Based Nursing. According to the "6S" model, systematically retrieve relevant evidence on bladder function exercises after orthotopic neobladder reconstruction surgery for bladder cancer, including clinical decisions, guidelines, expert consensus, evidence summaries, systematic reviews, and original research. UpToDate, BMJ Best Practice, Joanna Briggs Institute, National Guideline Clearinghouse, Guidelines International Network, American Urological Association , European Association of Urology, Chinese Urological Association, Yi Mai tong Guidelines Network, The Cochrane Library, PubMed, CINAHL, Web of Science, Embase, Sinomed, CNKI, VIP Database, Wanfang database were searched from the establishment of the database to May 2025. Results We included a total of 21 articles, involving 1 evidence summary, 1 expert consensus, 11 randomized controlled trials, and 8 quasi-experimental studies. A total of 39 pieces of evidence were identified, covering 11 key areas such as the importance of bladder function exercise, establish a multidisciplinary team for bladder function exercise, comprehensive preoperative assessment and guidance, urinary storage function training, urination habit training, urination method training, urinary control function training, daily self-management, social support and psychological care, health education, follow-up and effect evaluation. Conclusion This review summarizes the best evidence for the rehabilitation management of bladder function in patients with orthotopic neobladder can help standardize clinical practice. Healthcare providers should adjust this evidence based on the local medical environment, cultural background, obstacles and patient preferences. Implications for Nursing Practice This review provides guidance for clinical practice by integrating multidisciplinary care, comprehensive preoperative assessment, systematic bladder training, and robust psychosocial support. Additionally, it emphasizes nurse-led follow-up and personalized rehabilitation plans to enhance patients' functional recovery and quality of life after neobladder reconstruction.