Kidney Transplantation in a Patient With Hairy Cell Leukemia in Complete Remission: A Case Report

Hairy cell leukemia (HCL) is a rare, indolent B‐cell neoplasm characterized by the BRAF V600E mutation. Kidney transplantation in patients with active or prior hematologic malignancy represents a complex clinical scenario with limited evidence on current guidelines. We report the first documented case of a patient that while undergoing kidney transplant evaluation was diagnosed with classic HCL. He was treated with vemurafenib and rituximab and achieved complete remission (CR). He subsequently underwent successful kidney transplantation and has remained in sustained CR with stable allograft function at 22 months of follow‐up. This case highlights the importance of individualized multidisciplinary transplant decision‐making. Trial Registration : The authors have confirmed clinical trial registration is not needed for this submission.