Key result
Central obesity linked to high 10-year CHD risk in ~38% of women vs 0%.
Why the study?
The high prevalence of obesity among Jordanian women aged 30–50 years underscores the need for early cardiovascular risk assessment to support targeted preventive strategies, motivating an evaluation of the associations between general obesity, central obesity, cardiometabolic risk factors, and estimated 10-year CHD risk.
Does general and central obesity increase the estimated 10-year Framingham risk of coronary heart disease and cardiometabolic abnormalities in healthy Jordanian women aged 30–50 years?
Cross-Sectional (n=230)
No
Does general and central obesity increase the estimated 10-year Framingham risk of coronary heart disease and cardiometabolic abnormalities in healthy Jordanian women aged 30–50 years?
Among apparently healthy Jordanian women aged 30–50 years, high rates of general (39.1%) and central obesity (40.9%), along with smoking (47.0%), are strongly associated with adverse cardiometabolic profiles and a 17.4% prevalence of high estimated 10-year coronary heart disease risk.
Answers are grounded in this paper and cite their sources.
Highlights obesity as a correlate of elevated CHD risk estimates in Jordanian women; leaves open causal links and intervention effects.
Background Obesity is a well‐established modifiable risk factor for cardiovascular disease (CVD), particularly coronary heart disease (CHD). Its high prevalence among Jordanian women aged 30–50 years highlights the need for early cardiovascular risk assessment to support targeted preventive strategies. Objective To estimate the 10‐year risk of CHD among Jordanian women aged 30–50 years using the Framingham risk score (FRS) and to examine the associations between general obesity, central obesity, cardiometabolic risk factors, and estimated CHD risk. Methods A cross‐sectional study was conducted among 230 Jordanian women aged 30–50 years who were recruited using a multistage cluster sampling technique. Standardized anthropometric measurements, including body weight, height, and waist circumference (WC), were obtained to calculate body mass index (BMI) and waist‐to‐height ratio (WHtR). Blood pressure was measured according to standardized procedures, and fasting blood samples were analyzed to determine fasting blood glucose and lipid profile parameters. Smoking status and physical activity were assessed using structured questionnaires. The 10‐year risk of CHD was estimated using the FRS. Descriptive and inferential statistical analyses were performed to evaluate the associations between obesity indices and estimated CHD risk. Results General obesity was identified in 39.1% of participants, while 40.9% had central obesity based on WC (≥ 88 cm). Nearly half of the participants (47.0%) were current smokers, and 21.3% reported low levels of physical activity. According to the FRS, 66.1% of participants were classified as having low CHD risk, 16.5% as moderate risk, and 17.4% as high risk. Higher BMI and central obesity were significantly associated with elevated blood pressure, fasting blood glucose, triglyceride levels, and LDL cholesterol, as well as lower HDL cholesterol (all p < 0.001). Smoking, physical inactivity, and both general and central obesity were significantly associated with an increased estimated risk of CHD. Conclusion Jordanian women aged 30–50 years exhibited a substantial burden of both general and central obesity, accompanied by an increased estimated risk of CHD. These findings underscore the importance of routine cardiovascular risk assessment and comprehensive lifestyle interventions focusing on weight management, smoking cessation, and regular physical activity. Because the FRS has not been specifically validated in Jordanian women, the estimated absolute cardiovascular risk should be interpreted with caution.
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Alboqai et al. (2026) conducted a cross-sectional in General and central obesity and estimated 10-year coronary heart disease risk (n=230). Central obesity (waist circumference >= 88 cm) and general obesity (BMI >= 30 kg/m2) vs. Normal waist circumference (< 80 cm) and normal weight (BMI 18.5-24.9 kg/m2) was evaluated on High estimated 10-year hard coronary heart disease risk (>= 20%) based on the female-specific ATP III Framingham risk score (p=<0.001). Central obesity (WC >= 88 cm) and general obesity (BMI >= 30 kg/m2) were associated with high 10-year Framingham CHD risk in 38.3% and 36.7% of Jordanian women, respectively, vs 0% in normal groups.
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