Does candesartan alone or in combination with enalapril improve left ventricular remodeling compared to enalapril alone in patients with congestive heart failure?
Combining candesartan and enalapril provides greater benefit for preventing left ventricular remodeling in congestive heart failure than either drug alone.
Candesartan alone was as effective, safe, and tolerable as enalapril. The combination of candesartan and enalapril was more beneficial for preventing left ventricular remodeling than either candesartan or enalapril alone.
McKelvie et al. (Tue,) studied this question.