October 14, 2003
Reversal of Atrial Mechanical Dysfunction After Cardioversion of Atrial Fibrillation
Structured PICO
Do atrial pacing and isoproterenol reverse atrial mechanical stunning after cardioversion of atrial fibrillation?
P
Population
Subjects with atrial fibrillation (short-duration and long-duration) experiencing atrial mechanical stunning after cardioversion
I
Intervention
Atrial pacing at increased rates and isoproterenol
O
Outcome
Reversal of atrial mechanical stunningsurrogate
Atrial mechanical stunning after short-duration AF can be reversed by pacing and isoproterenol, indicating a functional contractile apparatus, while long-duration AF involves additional factors.
Abstract
Atrial pacing at increased rates and isoproterenol can reverse atrial mechanical stunning associated with short-duration AF. In contrast, long-duration AF is associated with an attenuated response to these maneuvers. These findings suggest a functional contractile apparatus in the mechanically remodeled atrium caused by AF; however, with longer durations of AF, additional factors may determine atrial mechanical function.
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Authors
Prashanthan Sanders
Electrophysiology
J
Joseph B. Morton
West Virginia University
P
Peter M. Kistler
Electrophysiology
Journals
Circulation
Actions
Institutions
The Royal Melbourne Hospital
References and Citations
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