May 20, 2003
Health Outcomes Associated With Various Antihypertensive Therapies Used as First-Line Agents
Structured PICO
Do low-dose diuretics prevent cardiovascular disease morbidity and mortality better than other first-line antihypertensive therapies?
P
Population
Patients requiring first-line antihypertensive therapy
I
Intervention
Low-dose diuretics
C
Comparator
Various other antihypertensive therapies
O
Outcome
Cardiovascular disease morbidity and mortalityhard clinical
Low-dose diuretics should be considered the standard first-line antihypertensive therapy for preventing cardiovascular morbidity and mortality.
Abstract
Low-dose diuretics are the most effective first-line treatment for preventing the occurrence of cardiovascular disease morbidity and mortality. Clinical practice and treatment guidelines should reflect this evidence, and future trials should use low-dose diuretics as the standard for clinically useful comparisons.
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Authors
B
Bruce M. Psaty
Brigham Young University
T
Thomas Lumley
Preventive Cardiology
Curt D. Furberg
Linköping University
Journals
JAMA
Actions
Institutions
University of Washington
Wake Forest University
Seattle University
References and Citations
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