Cells from the center and outer pathways of a reentrant circuit during ventricular tachycardia
Changes in effective refractory periods and stabilization of reentrysurrogate
Electrophysiological remodeling of sodium and calcium currents in different regions of a ventricular tachycardia circuit alters refractory periods in a way that stabilizes reentry.
Despite differences in INa and ICaL properties in cells of the center and outer pathways of a reentrant circuit, the resulting changes in effective refractory periods tend to stabilize reentry in this remodeled substrate.
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Shigeo Baba
Toyobo (Japan)
Wen Dun
Columbia University Irving Medical Center
Cándido Cabo
City University of New York
Circulation
City University of New York
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Baba et al. (Tue,) studied this question.
synapsesocial.com/papers/69d56e1d75589c71d767d3d4 — DOI: https://doi.org/10.1161/circulationaha.105.534784
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