October 1, 2003Open Access
Sirolimus-Eluting Stents versus Standard Stents in Patients with Stenosis in a Native Coronary Artery
Structured PICO
Does a sirolimus-eluting stent reduce restenosis and associated clinical events compared to standard stents in patients with stenosis in a native coronary artery?
P
Population
Patients with stenosis in a native coronary artery and complex coronary lesions
I
Intervention
Sirolimus-eluting stent
C
Comparator
Standard stents
O
Outcome
Rates of restenosis and associated clinical eventscomposite
Sirolimus-eluting stents are effective at reducing restenosis and associated clinical events in patients with complex coronary lesions.
Abstract
In this randomized clinical trial involving patients with complex coronary lesions, the use of a sirolimus-eluting stent had a consistent treatment effect, reducing the rates of restenosis and associated clinical events in all subgroups analyzed.
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Authors
Jeffrey W. Moses
Interventional Cardiology
Martin B. Leon
Columbia University Irving Medical Center
Jeffrey J. Popma
Interventional Cardiology
Journals
New England Journal of Medicine
Actions
Institutions
Cardiovascular Research Foundation
Vascular Institute of New York
References and Citations
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