Thallium-201 scintigraphy detected infarction in 93.8% of patients studied within 24 hours of symptom onset compared to 72.1% of those studied later (p<0.01).
Observational (n=200)
Does the timing of Thallium-201 scintigraphy affect its diagnostic usefulness in patients with acute myocardial infarction?
Thallium-201 scintigraphy is highly sensitive for detecting acute myocardial infarction, particularly when performed within the first 24 hours of symptom onset.
Absolute Event Rate: 93.75% vs 72.12%
p-value: p=<0.01
We examined the diagnostic usefulness of thallium-201 scintigraphy in 200 patients with acute myocardial infarction. The scintiscans showed a defect, suggesting infarction in 165. In all 44 patients studied iwthin six hours after onset of symptoms the scintiscans indicated a defect. Frequency of positive scans was significantly higher (90 of 96) in patients studied within 24 hours after onset than in those (75 of 104) studied later (p less than 0.01).
Wackers et al. (Thu,) conducted a observational in Acute myocardial infarction (n=200). Thallium-201 scintigraphy within 24 hours of symptom onset vs. Thallium-201 scintigraphy later than 24 hours was evaluated on Positive scan (defect suggesting infarction) (p=<0.01). Thallium-201 scintigraphy detected infarction in 93.8% of patients studied within 24 hours of symptom onset compared to 72.1% of those studied later (p<0.01).