Is any degree of albuminuria a risk factor for cardiovascular events, death, and heart failure in individuals with or without diabetes?
Individuals with or without diabetes mellitus (DM)
Albuminuria (measured by albumin-to-creatinine ratio [ACR])
Lower levels of albuminuria or no albuminuria
Cardiovascular events, death, and heart failurehard clinical
Any degree of albuminuria, even below the traditional microalbuminuria cutoff, is a risk factor for cardiovascular events in both diabetic and nondiabetic individuals.
Our results indicate that any degree of albuminuria is a risk factor for CV events in individuals with or without DM; the risk increases with the ACR, starting well below the microalbuminuria cutoff. Screening for albuminuria identifies people at high risk for CV events.
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Hertzel C. Gerstein
JAMA
McMaster University
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Hertzel C. Gerstein (Wed,) studied this question.
www.synapsesocial.com/papers/69effb6cafa91c76b5d0a8ac — DOI: https://doi.org/10.1001/jama.286.4.421