Does race/ethnicity affect the appropriate Lipoprotein(a) cutoff value for coronary heart disease risk assessment?
Lipoprotein(a) risk thresholds for coronary heart disease should be race-specific, with higher cutoffs (50 mg/dL) for white and Hispanic individuals compared to black individuals (30 mg/dL).
Our findings suggest that the 30 mg/dL cutoff for Lp(a) is not appropriate in white and Hispanic individuals, and the higher 50 mg/dL cutoff should be considered. In contrast, the 30 mg/dL cutoff remains suitable in black individuals. Further research is necessary to develop the most clinically useful Lp(a) cutoff values in individual races/ethnicities.
Guan et al. (Fri,) studied this question.