Does non-contrast T1 mapping correlate with biopsy-quantified diffuse myocardial fibrosis in patients with severe aortic stenosis?
Non-contrast T1 mapping correlates with histological fibrosis and may provide a useful non-invasive clinical assessment of diffuse myocardial fibrosis in patients with severe aortic stenosis.
Non-contrast T1 values are increased in patients with severe AS and further increase in symptomatic compared with asymptomatic patients. T1 values lengthened with greater LVMI and correlated with the degree of biopsy-quantified fibrosis. This may provide a useful clinical assessment of diffuse myocardial fibrosis in the future.
Bull et al. (Thu,) studied this question.