Why the study?
Does non-contrast T1 mapping correlate with biopsy-quantified diffuse myocardial fibrosis in patients with severe aortic stenosis?
Population
Patients with severe aortic stenosis (AS), including symptomatic and asymptomatic individuals
Comparison
Non-contrast T1 mapping vs Biopsy-quantified fibrosis (histology)
Design
Cross-sectional
Authors
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Supports non-contrast T1 as potential non-invasive fibrosis marker in severe AS; hypothesis-generating, requires prospective validation before clinical use.
Does non-contrast T1 mapping correlate with biopsy-quantified diffuse myocardial fibrosis in patients with severe aortic stenosis?
Non-contrast T1 mapping correlates with histological fibrosis and may provide a useful non-invasive clinical assessment of diffuse myocardial fibrosis in patients with severe aortic stenosis.
Bull et al. (2013) studied this question.
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