November 17, 2009Open Access
Advanced Heart Failure Treated with Continuous-Flow Left Ventricular Assist Device
Structured PICO
Does a continuous-flow left ventricular assist device improve survival free from stroke and device failure in patients with advanced heart failure compared to a pulsatile device?
P
Population
patients with advanced heart failure
I
Intervention
continuous-flow left ventricular assist device
C
Comparator
pulsatile device
O
Outcome
survival free from stroke and device failure at 2 yearscomposite
Continuous-flow LVADs provide superior 2-year survival free from stroke and device failure compared to pulsatile devices in patients with advanced heart failure.
Abstract
Treatment with a continuous-flow left ventricular assist device in patients with advanced heart failure significantly improved the probability of survival free from stroke and device failure at 2 years as compared with a pulsatile device. Both devices significantly improved the quality of life and functional capacity. (ClinicalTrials.gov number, NCT00121485.)
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Authors
M
Mark S. Slaughter
University of Louisville
Joseph G. Rogers
Heart Failure & Transplant
C
Carmelo A. Milano
Cardiac Surgery
Journals
New England Journal of Medicine
Actions
Institutions
The Ohio State University
Duke Medical Center
Johns Hopkins Hospital
References and Citations
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