Tricuspid valve avulsion combined with pulmonary artery stenosis provides a viable experimental canine model for producing chronic right-sided heart failure.
SummaryA form of progressive, chronic, “right-sided” cardiac failure has been produced in dogs by tricuspid valve avulsion and pulmonary artery stenosis. Three dogs so treated developed congestive failure with elevated auricular pressure and distended veins, decreased work tolerance, hepatomegaly, ascites, tachycardia at rest, and a relatively fixed heart rate during exercise. Studies of 2 of the hearts in the heart-lung preparation indicate clearly that cardiac insufficiency was present.
Barger et al. (Sun,) studied this question.