Does immediate PTCA reduce the combined occurrence of nonfatal reinfarction or death in patients with acute myocardial infarction compared with t-PA therapy?
Patients with acute myocardial infarction
Immediate PTCA (percutaneous transluminal coronary angioplasty)
t-PA (tissue plasminogen activator) therapy
Combined occurrence of nonfatal reinfarction or deathcomposite
Immediate PTCA provides better clinical outcomes than t-PA therapy for acute myocardial infarction by reducing reinfarction, death, and intracranial hemorrhage.
As compared with t-PA therapy for acute myocardial infarction, immediate PTCA reduced the combined occurrence of nonfatal reinfarction or death, was associated with a lower rate of intracranial hemorrhage, and resulted in similar left ventricular systolic function.
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Cindy L. Grines
Kevin F. Browne
Jean Marco
New England Journal of Medicine
Beaumont Hospital, Royal Oak
Allegheny General Hospital
Clinique Pasteur
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Grines et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d5767e62196bac97d9bb6a — DOI: https://doi.org/10.1056/nejm199303113281001
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