Is renal tubular resistance the primary driver for loop diuretic resistance in patients with acute heart failure?
Renal tubular resistance, rather than reduced diuretic delivery, is the primary driver of loop diuretic resistance in acute heart failure.
Defects at the level of the renal tubule are substantially more important than reduced diuretic delivery in determining diuretic resistance in patients with AHF.
Maaten et al. (Thu,) studied this question.
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