In a prospective cohort of 50 patients undergoing open-heart surgery, acute renal failure occurred in 10% of patients and was associated with factors such as cardiopulmonary bypass time and lower hematocrit.
Observational (n=50)
No
This observational study highlights the incidence of acute renal failure after open-heart surgery and identifies pre- and peri-operative variables associated with its development.
Background: Acute kidney injury (AKI) is one of the most serious complications during the postoperative period of cardiac surgery. Multiple variables predict the ARF after cardiac surgery. Objective of this study was to evaluate the significance of pre and peri-operative variables which may help in predicting the chances of developing ARF after cardiac surgery.Methods: This study was an observational, prospective study conducted among patients who were scheduled to undergo open heart surgery under cardiopulmonary bypass.Results: In total, 50 patients who underwent open-heart surgery, ARF was seen in 5 patients, with the incidence rate of 10%. Acute renal failure was present in one patient with ejection fraction 50. It was seen in 4 patients with 1-2 hrs of cardiopulmonary bypass and in 1 patient with >2 hrs of cardiopulmonary bypass. ARF was also seen in 4 patients with hematocrit between 22-26% and in 1 patient with >26%.Conclusions: The study provided a clinical variable score that can predict ARF after open-heart surgery. The score enhances the accuracy of prediction by accounting for the effect of all major risk factors of ARF.
Dhaulta et al. (Sat,) conducted a observational in Open heart surgery under cardiopulmonary bypass (n=50). Pre-operative and peri-operative risk factors vs. Patients without risk factors was evaluated on Acute renal failure (rise of >50% above baseline in serum creatinine on postoperative day 1 to 3). In a prospective cohort of 50 patients undergoing open-heart surgery, acute renal failure occurred in 10% of patients and was associated with factors such as cardiopulmonary bypass time and lower hematocrit.