November 17, 2021Open Access
View Full PaperDigoxin use in contemporary heart failure with reduced ejection fraction: an analysis from the Swedish Heart Failure Registry
Structured PICO
Does digoxin use improve mortality/morbidity in patients with contemporary heart failure with reduced ejection fraction?
P
Population
Patients with contemporary heart failure with reduced ejection fraction (HFrEF) from the Swedish Heart Failure Registry
I
Intervention
Digoxin
O
Outcome
Mortality/morbiditycomposite
In contemporary HFrEF, digoxin use is associated with lower mortality/morbidity in patients with atrial fibrillation, but higher mortality/morbidity in those without atrial fibrillation.
Abstract
The great majority of digoxin users had a history of AF. Digoxin use was associated with lower mortality/morbidity in patients with AF, but with higher mortality/morbidity in patients without AF.