Velocity encoded mitral valve inflow cine (MVI) preserved overall vessel sharpness compared to 4-chamber cine (30.5% vs 31.0%, p=0.63) and reduced inter-observer variability by 5.4% (p<0.0001).
Observational
Blinded observers
Does a velocity encoded mitral valve inflow cine (MVI) method improve image quality and reproducibility compared to the standard 4-chamber (4CH) cine method during coronary magnetic resonance angiography?
The MVI method is a technically feasible and more reproducible alternative to the standard 4CH method for determining cardiac rest periods during CMRA, while preserving vessel sharpness and image quality.
Absolute Event Rate: 30.5% vs 31%
p-value: p=0.63
A high temporal resolution, 4-chamber (4CH) cine is the standard method for determining cardiac rest periods during whole heart coronary magnetic resonance angiography (CMRA). We evaluated the image quality and reproducibility between the 4CH cine method and a novel approach using a velocity encoded mitral valve inflow cine (MVI). The goal of this study was to compare the quality of CMRAs utilizing MVI versus 4CH methods. Sharpness and vessel length for the LCA and RCA using each method were determined using Soap Bubble and two blinded observers independently assessed coronary image quality. Offline analysis on a separate, retrospective cohort (n = 25) was used to compare MVI and 4CH reproducibility. In the prospectively evaluated cohort there was no difference in overall vessel sharpness (4CH vs MVI mean ± SD) (31.0 ± 5.5% vs 30.5 ± 5.7%, p = .63), LCA vessel sharpness (30.0 ± 5.4% vs 31.1 ± 8.2%, p = .44), LCA length (4.7 ± 1.4 cm vs 4.6 ± 1.6 cm, p = .66), RCA vessel sharpness (32.1 ± 6.9% vs 31.1 ± 7.7%, p = .55), RCA length (5.51 ± 2.6 cm vs 5.95 ± 2.4 cm, p = .38), or image quality rating (2.66 vs 2.62, p = .80) between methods. In the retrospective cohort, the MVI method had 5.4% lower inter-observer variability (95% CI 3.7,7.2%, p < .0001) and 3.9% lower intra-observer variability (95% CI 2.4,5.4%, p < .0001) than the 4CH method. MVI is a technically feasible and more reproducible method to determine cardiac rest periods compared to 4CH while preserving vessel sharpness, vessel length & image quality.
Markus et al. (Sat,) conducted a observational in Coronary magnetic resonance angiography. Velocity encoded mitral valve inflow cine (MVI) vs. 4-chamber (4CH) cine was evaluated on Overall vessel sharpness (p=0.63). Velocity encoded mitral valve inflow cine (MVI) preserved overall vessel sharpness compared to 4-chamber cine (30.5% vs 31.0%, p=0.63) and reduced inter-observer variability by 5.4% (p<0.0001).
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