Presence of late gadolinium enhancement in 4 or more segments on cardiac MRI was associated with ventricular arrhythmias with a sensitivity of 73%, specificity of 76%, and AUC of 0.733.
Observational (n=57)
Hypertrophic cardiomyopathy (n=57)
Late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging
Occurrence of ventricular arrhythmias (VAs) — AUC 0.733
Effect estimate: AUC 0.733
This prospective observational study sought to correlate segmental late gadolinium enhancement (LGE) seen in cardiac magnetic resonance imaging with occurrence of ventricular arrhythmias (VAs) in patients with hypertrophic cardiomyopathy. LGE was assessed in a 17-segmental model of heart. Of 57 patients, VAs were present in 26.3% of patients and 10.5% had sustained ventricular tachycardia. LGE was present in 43.9% of patients. Presence of LGE in 4 or more segments was associated with VAs with a sensitivity of 73% and specificity of 76% with area under curve of 0.733 in C-statistics.
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Harikrishnan Gangadharakaimal
Sree Chitra Thirunal Institute for Medical Sciences and Technology
Nitin Parashar
All India Institute of Medical Sciences
Mukund A. Prabhu
Electrophysiology
Indian Heart Journal
Sree Chitra Thirunal Institute for Medical Sciences and Technology
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Gangadharakaimal et al. (Wed,) conducted a observational in Hypertrophic cardiomyopathy (n=57). Late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging was evaluated on Occurrence of ventricular arrhythmias (VAs) (AUC 0.733). Presence of late gadolinium enhancement in 4 or more segments on cardiac MRI was associated with ventricular arrhythmias with a sensitivity of 73%, specificity of 76%, and AUC of 0.733.
synapsesocial.com/papers/6a11d57f45487b7639a5658f — DOI: https://doi.org/10.1016/j.ihj.2023.08.001