May 16, 2024

Single-cell transcriptomes and chromatin accessibility of endothelial cells unravel transcription factors associated with dysregulated angiogenesis in systemic sclerosis

Key Points

Key points are not available for this paper at this time.

Abstract

Vasculopathy emerges early in systemic sclerosis (SSc) and links to endothelial cell (EC) injury and angiogenesis. Understanding EC transcriptomes and epigenomes is crucial for unravelling the mechanisms involved.

Bookmark

Cite This Study

Huang et al. (Thu,) studied this question.

synapsesocial.com/papers/68e69af9b6db643587620d4e https://doi.org/https://doi.org/10.1136/ard-2023-225415

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Vascular involvement in systemic sclerosis (scleroderma)2011 · 116 citations
2Arid5a Regulation and the Roles of Arid5a in the Inflammatory Response and Disease2019 · 62 citations
3Role of Transcription Factors in Angiogenesis2001 · 50 citations
4An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates2020 · 471 citations
5Prediction of organ involvement in systemic sclerosis by serum biomarkers and peripheral endothelial function.2019 · 21 citations

Bookmark