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May 16, 2024Annals of the Rheumatic Diseases

Single-cell transcriptomes and chromatin accessibility of endothelial cells unravel transcription factors associated with dysregulated angiogenesis in systemic sclerosis

Mengqi Huang Tracy Tabib Dinesh Khanna Shervin Assassi Robyn T. Domsic Robert Lafyatis

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Abstract

Vasculopathy emerges early in systemic sclerosis (SSc) and links to endothelial cell (EC) injury and angiogenesis. Understanding EC transcriptomes and epigenomes is crucial for unravelling the mechanisms involved.

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Cite This Study

Huang et al. (2024) studied this question.

synapsesocial.com/papers/68e69af9b6db643587620d4e https://doi.org/10.1136/ard-2023-225415

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