Identification of the Novel HLA‐DRB1*07:174 Allele by Third‐Generation Sequencing

Key Points

• The aim is to identify and characterize the new HLA-DRB1*07:174 allele.
• Utilized third-generation sequencing technology
• Focused on specific nucleotide substitutions
• Analyzed codon differences in exon 3
• HLA-DRB1*07:174 identified as differing from HLA-DRB1*07:01:01:01
• Difference due to a single nucleotide change in codon 112