What question did this study set out to answer?

This research aims to explore how pre-stroke cardiovascular disease risk affects cognitive decline and dementia after a stroke.

June 11, 2026Open Access

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Association of Pre-stroke Cardiovascular Risk With Post-stroke Cognitive Decline and Dementia

DLDeborah A. LevineUniversity of Michigan WHWan-Ling HsuUniversity of Michigan WYWen YeUniversity of Michigan

Key Points

This research aims to explore how pre-stroke cardiovascular disease risk affects cognitive decline and dementia after a stroke.
Examined the PREVENT 10-year ASCVD risk score before stroke
Analyzed its association with cognitive decline and dementia post-stroke
Controlled for pre-stroke cognitive status
Higher pre-stroke ASCVD risk scores correlate with intensified cognitive decline and increased dementia incidence post-stroke.
Specific metrics of cognitive decline and dementia rates related to varying ASCVD risk levels are reported.

Abstract

Stroke survivors have an elevated risk of cognitive decline and dementia. It is unclear how pre-stroke atherosclerotic cardiovascular disease (ASCVD) risk influences post-stroke cognitive decline and dementia. We examined the association between pre-stroke American Heart Association Predicting Risk of Cardiovascular Disease EVENTs (PREVENT) 10-year ASCVD risk score (which includes age and sex) and post-stroke cognitive decline and dementia, independent of pre-stroke cognition.

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Cite This Study

Levine et al. (Mon,) studied this question.

synapsesocial.com/papers/6a2a4fa380c8f91e7f39c874 https://doi.org/https://doi.org/10.1212/wn9.0000000000000083

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