September 10, 2025Open Access Figure S16 from TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma
Key Points
- TGFβ inhibition significantly enhances immune cell infiltration and reduces metastases in Ewing sarcoma models.
- Experimental results indicate improved survival rates for mice treated with TGFβ inhibition and radiotherapy.
- The approach involved assessing survival of mice treated with ± RER and ± radiation therapy.
- These findings suggest TGFβ inhibition during radiotherapy may improve outcomes for Ewing sarcoma, highlighting a potential therapeutic strategy.
Abstract
Figure S16. Survival of mice treated with ± RER and ± radiation therapy.
Daley et al. (Wed,) studied this question.
Figure S9 from TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma2025