To assess the effectiveness of a 10-year risk score in predicting lower-limb amputation and related major health events in individuals with type 1 diabetes.
Developed a risk score based on clinical and demographic factors.
Evaluated the predictive ability of the score over a 10-year period.
Identified outcomes including lower-limb amputation, kidney failure, and cardiovascular disease.
The risk score effectively identifies individuals at high risk for lower-limb amputation.
It also shows excellent predictive ability for kidney failure and cardiovascular disease.
Individuals identified as high-risk may benefit from targeted preventive measures.
Abstract
This newly developed 10-year LLA risk score achieved excellent ability to identify individuals with type 1 diabetes at high risk for LLA, kidney failure, CVD, and MACE.