Amine-cation-driven heteroannulation of halomaleimides with C–N cleavage: metal-free access to heterobicyclic frameworks

Key Points

• The aim is to achieve a mild and efficient method for synthesizing heterobicyclic frameworks.
• Utilized halomaleimides and quaternary enamines in the synthesis process.
• Focused on metal-free reaction conditions.
• Achieved synthesis in synthetically useful yields.
• Successfully synthesized 3,4-diamin-substituted maleimide heterobicycles.
• Yielded significant amounts of the desired heterobicyclic compounds.