Incidence and impact of remimazolam-induced paradoxical reactions in pediatric same-day bidirectional endoscopy: a randomized, controlled clinical trial | Synapse
February 22, 2026Minerva Anestesiologica1 citations
Incidence and impact of remimazolam-induced paradoxical reactions in pediatric same-day bidirectional endoscopy: a randomized, controlled clinical trial
The study aims to evaluate the incidence and impact of remimazolam-induced paradoxical reactions in children undergoing same-day bidirectional endoscopy.
Conducted a randomized, controlled clinical trial
Included children receiving different doses of premedication
Focused on measurement of paradoxical reactions during the procedure
Paradoxical reactions were more common in younger children
Lower premedication doses resulted in higher incidence of reactions
Paradoxical reactions did not negatively impact overall sedation or prognosis
Abstract
PR was more prevalent in the lower premedication dose group and younger children but did not adversely affect sedation or prognosis.