Optimized gradient of lyophilized platelet-rich plasma in biomimetic 3D-printed triphasic scaffold based on alginate and gelatin for osteochondral tissue engineering

Key Points

• Enhanced osteochondral tissue growth is observed in a biomimetic scaffold setup with optimized platelet-rich plasma.
• The analysis shows a marked increase in structural integrity and cell viability across 3D printed samples.
• Observational analysis using a gradient method improves tissue engineering potential through scaffold innovations.
• This approach highlights the necessity for further validation in clinical settings to optimize tissue regenerative strategies.