FNDC5/Irisin Mediates the Protective Effect of Resistance Exercise Against Myocardial Infarction-Induced Renal Injury by Improving Vascular Rarefaction in Mice

Key Points

• Irisin, a protein linked to exercise, plays a key role in reducing renal injury after myocardial infarction.
• Mice showed improved vascular rarefaction and kidney function following resistance exercise training.
• The study utilized a murine model to explore the effects of FNDC5 on organ protection.
• Findings highlight the potential of exercise-induced factors in preventing kidney damage after heart attacks.