LINC00963 Targets miR-495-3p to Regulate Pancreatic Cancer Cell Proliferation, Apoptosis, and Carboplatin Sensitivity

Key Points

• To investigate the role of LINC00963 in pancreatic cancer cell growth, apoptosis, and response to carboplatin treatment.
• Examined the downregulation of LINC00963 in pancreatic cancer cells
• Measured changes in miR-495-3p levels
• Assessed cell proliferation and apoptosis rates
• Evaluated sensitivity to carboplatin
• Downregulation of LINC00963 correlated with decreased cell proliferation
• Increased levels of miR-495-3p were observed upon LINC00963 downregulation
• Enhanced sensitivity to carboplatin treatment was noted in pancreatic cancer cells after LINC00963 knockdown