Tenecteplase versus alteplase as bridging therapy before endovascular treatment in acute ischemic stroke due to Basilar artery occlusion: a systematic review and meta-analysis.

Key Points

• The study aims to compare the effectiveness of tenecteplase and alteplase as bridging therapies in acute ischemic stroke due to basilar artery occlusion.
• Conducted a systematic review and meta-analysis
• Compared outcomes of tenecteplase and alteplase as bridging therapies
• Evaluated early and final reperfusion rates, hemorrhagic risk, and mortality
• Tenecteplase improved early and final reperfusion rates
• No increase in hemorrhagic risk or mortality with tenecteplase
• Functional outcomes with tenecteplase were comparable to alteplase