What question did this study set out to answer?

To evaluate a nonextraction intervention for managing self-injurious behavior in children with Lesch-Nyhan syndrome.

March 12, 20260 citations

Nonextraction solution for self-injurious behavior in children with Lesch-Nyhan syndrome: a retrospective case series with up to 14 years of follow-up.

KEKobi EfratHebrew University of Jerusalem OJOri Ben Joya PGProf David GozalMarshall Health

Key Points

To evaluate a nonextraction intervention for managing self-injurious behavior in children with Lesch-Nyhan syndrome.
Retrospective case series design
Follow-up period of up to 14 years
Focus on conservative intraoral techniques
Implementation by dentists trained in special care dentistry
Effective management of oral self-injurious behavior observed
Technique proved reversible compared to traditional extractions
Long-term functional outcomes maintained in experienced clinical settings

Abstract

This conservative, fully intraoral approach may represent an effective and reversible alternative to irreversible dental extractions for managing oral SIB in patients with LNS, particularly when implemented in experienced clinical settings. The technique appears most appropriate for dentists trained in special care or hospital-based dentistry to ensure safety, comfort, and long-term functional outcomes.

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